Relief valves on endosomes

Description:

Relief valves on endosomes

This 3D model represents the structure and mode of action of a membrane transporter of polyamines present in the membranes on organelles such as endoscopes and lysosomes. In this case the authors explain how the functional proteins (right) can facilitate release of the polyamides in the cytoplasm and mutations int he transporter can lead to malfunction (left) and accumulation of the molecules in the organelle.

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Author:

Dorotea Fracchiolla

Year:

2022

Technique:

Clay and gouache