PI3K-WIPI2 feedback loop activates LC3 lipidation

Description:

PI3K-WIPI2 feedback loop activates LC3 lipidation

This illustration highlights one of the most important reactions occurring during autophagosome formation. The illustration and the reactions have to be read from left to right. One after the other each molecule comes in place on the membrane (yellow) to perform its task, in a timely manner. The mechanism by which this chain of reactions is made fast and efficient was discovered recently and presented in this article.

Printed copy on sale
(different sizes)

Author:

Dorotea Fracchiolla

Year:

2020

Technique:

Pastels and ink